Matt Wilsey

Matt is a Silicon Valley angel investor and advisor. Previously, Matt was Co-Founder and Chief Revenue Officer of CardSpring, a payment infrastructure company that was acquired by Twitter.  Prior to CardSpring, Matt ran West coast sales and business development for  He was responsible for building Howcast’s instructional content library, distribution network, and strategic relationships.  Before Howcast, Matt worked for Kohlberg Kravis Roberts (KKR) on the Capital Markets team focused on new product development, capital raising, and investor relations.  Prior to that, Matt spent five years as Co-Founder and Vice President of Business Development at, where he was responsible for all content and distribution deals.

He started his career serving in various roles at the White House and the Department of Defense.  Matt became a rare disease hunter and advocate after his daughter Grace was born with NGLY1 Deficiency.  He has since funded over 40 scientists at 7 medical centers in 3 countries with the sole purpose of curing the disease. Matt holds a BA from Stanford University and a MBA from Stanford’s Graduate School of Business.  In addition to Global Genes, Matt sits on the Board of Directors of the Grace Wilsey Foundation where he is President, The Lucile Packard Foundation for Children’s Health, the EveryLife Foundation for Rare Diseases, and Perlstein Lab.

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