I ended 2014 with a “year in tweets” post. Today, I inaugurate the “last month in tweets” series as a fun and hopefully informative way to summarize our progress. Let’s dive right in.
A hearty PLab welcome to Alec Ludin, our new lab tech! @IyerSangeetha has him pouring plates already. pic.twitter.com/aCblPQm8vG
— Perlara (@PerlaraPBC) January 2, 2015
We started the new year by welcoming our newest member, Alec. Alec is working with Sangeetha to scale up our worm efforts.
Getting ready to commence the NPC HTS campaign. Here's the Fly Team in action. pic.twitter.com/UU3OSwHqpy
— Perlara (@PerlaraPBC) January 5, 2015
Tom and Tamy got the NPC fly screen up and running in earnest after months of careful optimization. Here they are at our liquid handling station preparing screening plates.
Our med chem advisor @JohnTuckerPhD is in lab today reviewing screening hits with us. No ugly structures so far! pic.twitter.com/oSdzGNyh0d
— Perlara (@PerlaraPBC) January 14, 2015
Our med chem advisor John visited us one day during #JPM15 week. Here he is explaining to us how compounds get bulkier over the course of drug development.
#OpenScience Challenge 1 to all lean biotech startups: share your 2014 budget @QB3 @JNJInnovation @labcentral @uBiome pic.twitter.com/pDvCHnbOuj
— Perlara (@PerlaraPBC) January 20, 2015
With tax season afoot, we crunched our 2014 financials. In the spirit of Open Science, we challenged other lean biotech startups to share last year’s budget numbers. (So far, no takers. But we hope other companies start to follow suit soon).
Yeast screen reproducibility pic.twitter.com/RGzXU0m67h
— Perlara (@PerlaraPBC) January 28, 2015
Nina and Kiran started to analyze the yeast screen data, which started to flow in right before the holidays. Here’s one of the sanity checks they ran: comparing two technical replicates.
1,000 compounds screened in this batch. Approaching 10,000 compounds screened this month. pic.twitter.com/xnoJHJxw7D
— Perlara (@PerlaraPBC) January 30, 2015
The first full month of multi-model-organism screening was productive. As evidence here’s a stack of scored fly plates.