Author: Sangeetha Iyer

Mouse models of NPC

Mouse models of NPC

Now that we’ve completed our screen in all of our invertebrate models of Niemann Pick Type C (NPC) disease, it’s time for us to switch gears to the higher models of NPC. We are in the process of moving our validated screen hits for additional testing in a...
2015 worm meeting recap

2015 worm meeting recap

This recap is a tad bit late- I’ve been meaning to write about my last conference visit. I was at the 20th International C. elegans meeting held at UCLA from June 24th-28th 2015. Below are the highlights of the meeting. Disclaimer: This post is not meant to...
World Orphan Drug Congress recap

World Orphan Drug Congress recap

I attended my first World Orphan Drug Congress last week in Washington, D.C. It was a lovely time to be in DC, cherry blossoms in the air. The meeting itself was held at the Hilton in the heart of downtown. With over 700 attendees (or so I was told), there was...
A worm screen for Niemann-Pick C

A worm screen for Niemann-Pick C

It’s soon going to be one year since we started screening for drug candidates that slow or reverse the progress of Niemann-Pick C disease in simple animal models. The last six months here at the Perlstein Lab have been especially busy. We are now knee deep into the...
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