by Ethan Perlstein | Jul 21, 2016 | Blogposts, Science |
Last month I traveled to Tucson for my third consecutive Ara Parseghian Medical Research Foundation meeting for Niemann-Pick Type C/NPC. In 2014 at my first APMRF meeting, which was hosted in South Bend at Notre Dame University, I was a newcomer to the NPC community...
by Ethan Perlstein | Apr 10, 2016 | Blogposts, Science |
Five months ago we introduced PERL101, one of our lead compounds for Niemann-Pick Type C (NPC) disease, in Part One. Here in Part Two we pick up the thread. On this journey we’ve progressed from nematodes to patient cells to mice with an unoptimized primary...
by Tamy Portillo Rodriguez | Mar 31, 2016 | Blogposts, Uncategorized |
Dimethly Sulfoxide, commonly known as DMSO, is a small molecule composed of two methyl groups attached to a Sulfur with an Oxygen (C2H6OS). It was the production of cheaper paper that led to the discovery of this colorless liquid in the 19th Century, but it was its...
by Sangeetha Iyer | Mar 11, 2016 | Blogposts |
Today’s post will focus on the vision for PLab. Let’s start with a basic statistical concept- long tail distribution. While this form of frequency distribution has been around since the 1940’s, it gained prominence in fields outside of insurance and...
by Tom Hartl | Oct 7, 2015 | Blogposts |
Lipids are stored in cellular locales called “lipid droplets.” The lipid droplet surface is a lipid monolayer coated with specific proteins. The best known lipid droplet surface proteins are “PAT” (Perilipin, ADRP and TIP47) domain proteins, or “Perilipins.” Inside...
by Ethan Perlstein | Feb 28, 2015 | Blogposts |
On behalf of the PLab team, I would like to wish everyone a happy Rare Disease Day 2015! I hope you all will take a few minutes today to appreciate that 1 in 12 people on Earth is affected by a rare disease. In the spirit of raising awareness about rare diseases,...
