The Ark
A blog about our science, the rare disease community and PerlQuests
September in tweets
Last month we achieved a major scientific milestone -- our first mouse...
Perlstein Lab Burn Rate through Q3 2015
At Perlstein Lab, we're interested in sharing our experiences so other young biotech...
Conservation of Fat Storage and Mobilization in Drosophila
Lipids are stored in cellular locales called “lipid droplets.” The lipid droplet...
August in tweets
Coinciding with the end of summer, we wrapped up the hit validation phase of our NPC...
Detoxing Drosophila
Our medicinal chemistry advisor and pharm/tox consultant have asked me, “Do flies...
Mouse models of NPC
Now that we've completed our screen in all of our invertebrate models of Niemann Pick...
July in tweets
July marked the transition from the primary screening phase of our Niemann-Pick C...
The Niemann-Pick C/Ebola connection
For this post we are going to take a slight detour and talk about something related...
June in tweets
Last month's highlight was that we completed the primary screening phase of our NPC...
Why do Purkinje cells die in NPC disease?
Niemann-Pick C (NPC) is a tragic neurodegenerative disease that is often referred to...
2015 worm meeting recap
This recap is a tad bit late- I've been meaning to write about my last conference...
May in tweets
Last month we were diligently completing the primary screening phase of our NPC...
