by Ethan Perlstein | Sep 10, 2015 | Last Month in Tweets |
Coinciding with the end of summer, we wrapped up the hit validation phase of our NPC lead discovery program. In 9 months, we whittled 50,o00 lead-like library compounds down to ~1,000 primary screening hits, which in turn we further winnowed down to ~100 fully...
by Ethan Perlstein | Aug 14, 2015 | Last Month in Tweets |
July marked the transition from the primary screening phase of our Niemann-Pick C drug discovery campaign to the hit validation phase. And lots more happenings in and around the lab. Our Med Chem advisor @JohnTuckerPhD is in the lab today reviewing hits from our NPC...
by Ethan Perlstein | Jul 18, 2015 | Last Month in Tweets |
Last month’s highlight was that we completed the primary screening phase of our NPC lead program. Let’s take a closer look at how summer started at PLab. Prices of orphan drugs for monogenic diseases are skyrocketing while approvals are flat — both...
by Ethan Perlstein | Jun 16, 2015 | Last Month in Tweets |
Last month we were diligently completing the primary screening phase of our NPC campaign: 50,000 compounds across 3 models in 6 months. Our NPC worm screen is nearing the home stretch. pic.twitter.com/eBOTpUq1N9 — Perlara (@PerlaraPBC) May 1, 2015 Team Worm...
by Ethan Perlstein | May 11, 2015 | Last Month in Tweets |
In April we crossed the midway point of our Niemann-Pick C multi-model HTS campaign. It was also Tamy’s first month as a full-time PLabber. Here she is with Tom scoring fly plates: Team Fly is scoring plates for the NPC screen on a Friday afternoon. That's...
