by Sangeetha Iyer | Feb 6, 2018 | Niemann-Pick Type A |
In December of 2016, Perlara partnered with Wylder Nation to initiate an NPA PerlQuest, a research and drug discovery program for Niemann Pick Type A disease. If you’ve been following our blog, you’ve kept up with our fly team’s efforts in...
by Ethan Perlstein | Jul 21, 2016 | Blogposts, Science |
Last month I traveled to Tucson for my third consecutive Ara Parseghian Medical Research Foundation meeting for Niemann-Pick Type C/NPC. In 2014 at my first APMRF meeting, which was hosted in South Bend at Notre Dame University, I was a newcomer to the NPC community...
by Ethan Perlstein | Nov 15, 2015 | Perlara science |
PERL101 is one of our lead compounds for Niemann-Pick C. We discovered it in a whole animal screen for small molecules that suppress the delayed onset of adulthood in NPC mutant nematode larvae. The path from primary screening hit to mouse validation studies usually...
by Sangeetha Iyer | Jul 7, 2015 | Science |
This recap is a tad bit late- I’ve been meaning to write about my last conference visit. I was at the 20th International C. elegans meeting held at UCLA from June 24th-28th 2015. Below are the highlights of the meeting. Disclaimer: This post is not meant to...
by Sangeetha Iyer | Mar 10, 2015 | Science |
It’s soon going to be one year since we started screening for drug candidates that slow or reverse the progress of Niemann-Pick C disease in simple animal models. The last six months here at the Perlstein Lab have been especially busy. We are now knee deep into the...
