by Nina DiPrimio | Jul 29, 2015 | Science |
For this post we are going to take a slight detour and talk about something related to Niemann-Pick C, filovirus infection. I am personally interested in the topic because of my love of viruses – plug for the highly informative TWiV (This Week in Virology)...
by Nina DiPrimio | May 26, 2015 | Science |
There are many research examples of yeast genes that were replaced by human orthologs for protein characterization, some of which with direct human disease relevance. One excellent example is out of Berkeley by researchers from the Rine lab published in 2012 where...
by Nina DiPrimio | Apr 7, 2015 | Science |
For those who have read our posts before and follow us on Twitter, you know we are using various model organisms such as fly, yeast and worm to discover novel therapeutics for a subset of rare genetic diseases. But once we find those potential drug candidates, how do...
![Yeast model of Mendelian mitochondrial diseases]()
by Nina DiPrimio | Feb 1, 2015 | Science |
Using yeast as a model organism to study human disease is not a new concept. Yeast are useful for this purpose for many reasons as discussed in a previous post, but potentially of most importance is that yeast cell biology is similar to that of mammalian cells, and...
by Nina DiPrimio | Oct 17, 2014 | Science |
If you go to clinicaltrial.gov, one of the only websites for up-to-date clinical trial information, and search for Niemann-Pick Type C (NP-C), you will notice a small set of trials in various stages of development. Some of the trials are focused on better...
