The Ark
A blog about our science, the rare disease community and PerlQuests
A fly screen for Niemann-Pick C
We are currently carrying out screens to find small molecules that could one day...
Lean Biotech Startup Burn Rate
Tracking expenses by the day and month is critical to estimating your runway as a...
January in tweets
I ended 2014 with a "year in tweets" post. Today, I inaugurate the "last month in...
Yeast model of Mendelian mitochondrial diseases
Using yeast as a model organism to study human disease is not a new concept. Yeast...
What is a precision orphan drug?
To cap off our Niemann-Pick C disease blog series -- here are parts 1, 2, and 3 --...
Lean biotech startup
PLab fits the mold of a lean startup but with a biotech twist. Over the course of...
2014 in review
Perlstein Lab PBC the company was officially born in February 2014. What have we...
A worm model of Niemann-Pick C
Niemann-Pick C disease is an inherited autosomal recessive disorder typified by a...
Biotech startup advice: how to save money while lab shopping for chemicals
To be lean with your biotech startup spending, you need to be informed and...
A yeast model of Niemann-Pick C
If you go to clinicaltrial.gov, one of the only websites for up-to-date clinical...
How to negotiate and shop for expensive lab equipment
The Perlstein Lab experimental design required the purchase of several pieces of...
A fly model of Niemann-Pick C
Scientists utilize an array of organisms to gain insight into the mechanisms...
