by Sangeetha Iyer | Feb 6, 2018 | Niemann-Pick Type A |
In December of 2016, Perlara partnered with Wylder Nation to initiate an NPA PerlQuest, a research and drug discovery program for Niemann Pick Type A disease. If you’ve been following our blog, you’ve kept up with our fly team’s efforts in...
by Jessica Lao | Jan 29, 2018 | PMM2-CDG |
A goal of Stage 1 of our PMM2-CDG PerlQuest with Maggie’s Cure is to identify yeast models that are suitable for use in screens for small molecules that rescue PMM2 deficiency. As described below, we successfully developed screen-ready yeast models that mirror two...
by Joshua Mast | Jan 22, 2018 | Niemann-Pick Type A |
A few months ago, Taryn Sumabat blogged about development of a fly model of a Niemann-Pick Type A Disease. Here I’ll remind you of the progress she described, and update you on our more recent work. If you remember, the two main objectives for this phase of our NPA...
by Ethan Perlstein | Jan 19, 2018 | NGLY1 |
Earlier this week I was alerted on Twitter (where else?) to a new NGLY1 paper from Dr. Clement Chow’s lab at the University of Utah titled: “Transcriptome and functional analysis in a Drosophila model of NGLY1 deficiency provides insight into therapeutic approaches,”...
by Tamy Portillo Rodriguez | Nov 1, 2017 | Perlara science |
Perlara’s high throughput screen progress in Mucolipidosis IV (MLIV) flies… In this blog post, I’ll tell you about Perlara’s high throughput screen progress in MLIV flies. Last year, Tom Hartl reviewed some details of MLIV disease biology and described how...
