by Tom Hartl | Jul 15, 2015 | Science |
Niemann-Pick C (NPC) is a tragic neurodegenerative disease that is often referred to as childhood Alzheimer’s disease. 95% of patients with NPC carry mutations in the npc1 gene, which codes for the Npc1 protein. Npc1 resides in lysosomes and is necessary for...
by Tom Hartl | Feb 24, 2015 | Science |
We are currently carrying out screens to find small molecules that could one day become a Niemann-Pick Type C (NPC) therapy. Patients with NPC carry mutant, or defective, copies of the npc1 gene. Like many human disease genes, the npc1 gene also exists in fruit flies....
