![Clinical relevance of a Drosophila model of Niemann-Pick C]()
by Tom Hartl | Jun 2, 2016 | Science |
Niemann-Pick type C (NPC) is a tragic childhood neurodegenerative disease. The majority of NPC cases (95%) are caused by mutations in the npc1 gene. Npc1 is a late endosomal/lysosomal (LEL) protein that is necessary for proper lipid trafficking. When Npc1 is...
by Tom Hartl | Sep 25, 2014 | Science |
Scientists utilize an array of organisms to gain insight into the mechanisms underlying disease. Among the most commonly used organisms is the fruit fly, Drosophila melanogaster. There are three main reasons that the fly is a terrific organism to study human diseases....
by Jun Axup | Jul 15, 2014 | Science |
Lysosomes are small organelles within cells that are responsible for breaking down and recycling cellular material, such as proteins, lipids, sugars – and even entire cellular compartments – that are damaged or worn out. This essential task is carried out...
