by Ethan Perlstein | May 15, 2016 | Last Month in Tweets |
We kicked off April with Tamy’s first post on the PLab blog. She and Tom have been working hard to launch our Drosophila NGLY1 HTS campaign. Tamy describes an unexpected challenge we encountered during assay development. DMSO and Drug Discovery...
by Ethan Perlstein | Mar 26, 2016 | Last Month in Tweets |
“Last month in tweets” took a hiatus in the first quarter of 2016, but now it’s back! Why the break? The answer is Y Combinator. On January 4th, PLab was accepted into YC’s Winter 2016 batch. The all-consuming 3-month startup accelerator took...
by Ethan Perlstein | Dec 28, 2015 | Last Month in Tweets |
Feels like the last 12 months went by in a flash! When I wrote this post a year ago, we were just getting started in the lab but we had ambitious plans for the year to come. We set two big goals for 2015. First, to complete a two-species (nematode and fruit fly),...
by Ethan Perlstein | Nov 13, 2015 | Last Month in Tweets |
Over the summer we completed the hit-to-lead phase of our NPC discovery program, and in the fall we commenced mouse validation studies with PERL101, our most promising hit from the nematode and fly primary screens. First mouse PK data (IV and PO) are in! —...
by Ethan Perlstein | Oct 20, 2015 | Last Month in Tweets |
Last month we achieved a major scientific milestone — our first mouse pharmacokinetics (PK) data show metabolic stability of our most promising lead compound. We were busy with conference travel, and we started rolling out blogs on a more consistent basis. The...
